Triaziquone

Triaziquone

SCHEMBL15513613

COCOCCN.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
STAT3 P40763 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DNMT1 P26358 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL9025980 0.89 TP53 (0.33) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL610295 0.84 DNMT1 (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL10379983 0.82 DNMT1 (0.41) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL2160619 0.82 DNMT1 (0.41) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL11416072 0.81 DNMT1 (0.40) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL11644813 0.80 DNMT1 (0.35) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL33439 0.79 HTT (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL9068031 0.79 TP53 (0.37) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL3172445 0.78 DNMT1 (0.33) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL600168 0.78 DNMT1 (0.40) TP53MAPTSTAT3HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140072914-A1 METHODS FOR MANUFACTURING RESIN STRUCTURE AND MICRO-STRUCTURE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-03-13 US disclosed