SCHEMBL15514432

SCHEMBL15514432

C=CC(OC(C=C)c1ccc(NC)cc1)c1ccc(NC)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.36
TSHR P16473 1/20 0.34
ALDH1A1 P00352 2/20 0.31
RECQL P46063 2/20 0.31
HSD17B10 Q99714 2/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
HIF1A Q16665 1/20 0.31
KIF11 P52732 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15515041 0.77 ALDH1A1 (0.48) TSHRALDH1A1RECQLHSD17B10CYP3A4
SCHEMBL28381315 0.77 CHRNA7 (0.43) ALDH1A1
SCHEMBL10873257 0.73 CA1 (0.46) TSHRALDH1A1CA12CA1CA2
SCHEMBL396233 0.73 SMN1; SMN2 (0.49) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL8407914 0.72 MEN1 (0.36) APPTSHRALDH1A1TP53CYP3A4
SCHEMBL9809375 0.72 TSHR (0.38) TSHRALDH1A1HSD17B10CA1CA2
SCHEMBL252297 0.72 CYP3A4 (0.37) TSHRALDH1A1HSD17B10TP53CYP3A4
SCHEMBL10493431 0.68 ALDH1A1 (0.33) TSHRALDH1A1HSD17B10TP53CYP3A4
SCHEMBL7785443 0.68 ALDH1A1 (0.47) TSHRALDH1A1HSD17B10TP53CYP3A4
SCHEMBL2495683 0.68 TSHR (0.48) APPTSHRALDH1A1RECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9035292-B2 Organic thin-film transistor insulating layer material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-19 US disclosed
US-20140070205-A1 ORGANIC THIN-FILM TRANSISTOR INSULATING LAYER MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-13 US disclosed