SCHEMBL396233

SCHEMBL396233

C=CC(OC(C=C)c1ccc(S(=O)(=O)NC)cc1)c1ccc(S(=O)(=O)NC)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.49
LMNA P02545 4/20 0.49
HTT P42858 2/20 0.49
GAA P10253 1/20 0.47
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA3 P07451 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA13 Q8N1Q1 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
ALDH1A1 P00352 5/20 0.43
NR3C2 P08235 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
DRD1 P21728 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL398361 0.77 CA2 (0.46) HTTCA12CA1CA2CA3
SCHEMBL396371 0.77 ALDH1A1 (0.49) SMN1; SMN2LMNAHTTGAAALDH1A1
SCHEMBL7629070 0.73 SMN1; SMN2 (0.80) SMN1; SMN2LMNAHTTGAACA12
SCHEMBL15514432 0.73 APP (0.36) CA12CA1CA2ALDH1A1KIF11
SCHEMBL1545593 0.72 CA12 (0.63) SMN1; SMN2LMNAHTTGAACA12
SCHEMBL1494528 0.71 SMN1; SMN2 (0.57) SMN1; SMN2LMNAHTTGAACA12
SCHEMBL5649208 0.70 SMN1; SMN2 (0.52) SMN1; SMN2LMNAHTTGAACA12
SCHEMBL28381315 0.70 CHRNA7 (0.43) SMN1; SMN2GAAALDH1A1NPC1MAPT
SCHEMBL29039499 0.69 SMN1; SMN2 (0.55) SMN1; SMN2LMNAHTTGAACA12
SCHEMBL18702879 0.69 SMN1; SMN2 (0.55) SMN1; SMN2LMNAHTTGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed