Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422477 | 1.00 | CYP19A1 (0.44) | CYP19A1HSD17B1SHBGSLC22A1ALDH1A1 | |
| SCHEMBL2361537 | 0.84 | HSD17B1 (0.39) | CYP19A1HSD17B1SHBGSERPINA6MEN1 | |
| SCHEMBL6832271 | 0.83 | CYP19A1 (0.63) | CYP19A1SHBGALDH1A1SERPINA6MEN1 | |
| SCHEMBL8083229 | 0.83 | CYP19A1 (0.63) | CYP19A1SHBGALDH1A1SERPINA6MEN1 | |
| SCHEMBL1422567 | 0.80 | CYP19A1 (0.69) | CYP19A1SHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL11629995 | 0.80 | CYP19A1 (0.69) | CYP19A1SHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL22845080 | 0.80 | CYP19A1 (0.69) | CYP19A1SHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL20851687 | 0.80 | CYP19A1 (0.69) | CYP19A1SHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL16661457 | 0.80 | CYP19A1 (0.69) | CYP19A1SHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL11629999 | 0.80 | CYP19A1 (0.69) | CYP19A1SHBGSLC22A1ALDH1A1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892909-A1 | PROCESS FOR PREPARING 11 -METHYLENE-18-METHYL-ESTR-4-EN-3, 17- DIONE, USEFUL AS INTERMEDIATE COMPOUND FOR THE SYNTHESIS OF MOLECULES HAVING A PHARMACOLOGICAL ACTIVITY | Industriale Chimica S.R.L. (IT) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014037873-A1 | PROCESS FOR PREPARING 11 -METHYLENE-18-METHYL-ESTR-4-EN-3, 17- DIONE, USEFUL AS INTERMEDIATE COMPOUND FOR THE SYNTHESIS OF MOLECULES HAVING A PHARMACOLOGICAL ACTIVITY | INDUSTRIALE CHIMICA S.R.L. (IT) | 2014-03-13 | — | — | WO | disclosed |