Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SHBG | P04278 | 3/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832271 | 1.00 | CYP19A1 (0.63) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL3658066 | 0.87 | CYP19A1 (0.63) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL7702309 | 0.87 | CYP19A1 (0.63) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL8209833 | 0.84 | CYP19A1 (0.59) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL9634694 | 0.83 | CYP19A1 (0.58) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL15515737 | 0.83 | CYP19A1 (0.44) | CYP19A1LMNASHBGSERPINA6ALDH1A1 | |
| SCHEMBL9634417 | 0.83 | CYP19A1 (0.58) | CYP19A1LMNASHBGSERPINA6PMP22 | |
| SCHEMBL1422477 | 0.83 | CYP19A1 (0.44) | CYP19A1LMNASHBGSERPINA6ALDH1A1 | |
| SCHEMBL3660111 | 0.83 | CYP19A1 (0.55) | CYP19A1MAPK1HSD17B10TSHRCYP3A4 | |
| SCHEMBL7757073 | 0.83 | CYP19A1 (0.44) | CYP19A1LMNASHBGSERPINA6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042355-A1 | 11BETA-HALOGEN-7ALPHA-SUBSTITUTED ESTRATRIENES, METHOD FOR PRODUCING PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11BETA-HALOGEN-7ALPHA-SUBSTITUTED ESTRATRIENES AND USE OF THE SAME FOR PRODUCING MEDICAMENTS | Schering Aktiengesellschaft (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033855-A1 | 11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES, METHOD FOR PRODUCING PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11β-HALOGEN-7α-SUBSTITUTED ESTRATRIENES AND USE OF THE SAME FOR PRODUCING MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-08 | — | — | WO | disclosed |
| EP-0920441-A1 | 7ALPHA-(EPSILON-AMINOALKYL)-ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7ALPHA-(EPSILON-AMINOALKYL)-ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007740-A1 | 7α-(κ-AMINOALKYL)ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7α-(κ-AMINOALKYL)ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |
| WO-1993025569-A1 | OESTRADIOL PRODRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-12-23 | — | — | WO | disclosed |