Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrogen SCHEMBL27371697 | 0.97 | PDE7A (0.61) | PDE7AL3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL10712446 | 0.87 | MAPT (0.64) | PDE7AL3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL14656523 | 0.86 | ALDH3A1 (0.58) | PDE7AL3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL26125825 | 0.85 | ALDH1A1 (0.56) | PDE7AL3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL10853042 | 0.84 | PDE7A (0.51) | PDE7AL3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL3840810 | 0.84 | MAPT (0.54) | PDE7AL3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL11455085 | 0.84 | PDE7A (0.54) | PDE7AL3MBTL1MAPTMAPK1NPSR1 | |
| SCHEMBL4129918 | 0.83 | L3MBTL1 (0.54) | PDE7AL3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL5705175 | 0.83 | L3MBTL1 (0.67) | L3MBTL1MAPTALDH1A1MAPK1NPSR1 | |
| SCHEMBL11017748 | 0.82 | TDP1 (0.67) | PDE7AL3MBTL1MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103601684-B | 5-arylseleno benzimidazoles compound and uses thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| EP-1590332-B1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND THEIR DERIVATIVES. | UNIV DELHI (IN) | 2011-04-27 | — | — | EP | claimed |
| EP-1590332-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | University of Delhi (IN) | 2005-11-02 | — | — | EP | claimed |
| WO-2004063170-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | UNIVERSITY OF DELHI (IN) | 2004-07-29 | — | — | WO | claimed |
| CN-103601684-B | 5-arylseleno benzimidazoles compound and uses thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103601684-A | 5-arylselenobenzimidazole compound and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-02-26 | — | — | CN | disclosed |
| EP-1590332-B1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND THEIR DERIVATIVES. | UNIV DELHI (IN) | 2011-04-27 | — | — | EP | disclosed |
| EP-1590332-B1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND THEIR DERIVATIVES. | UNIV DELHI (IN) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010126922-A1 | BENZIMIDAZOLECARBOXAMIDES AS INHIBITORS OF FAK | GLAXOSMITHKLINE LLC (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010126922-A1 | BENZIMIDAZOLECARBOXAMIDES AS INHIBITORS OF FAK | GLAXOSMITHKLINE LLC (US) | 2010-11-04 | — | — | WO | disclosed |
| EP-1590332-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | University of Delhi (IN) | 2005-11-02 | — | — | EP | disclosed |
| EP-1590332-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | University of Delhi (IN) | 2005-11-02 | — | — | EP | disclosed |
| US-4011320-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4005202-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-4002640-A | ANTIFUNGAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-11 | — | — | US | disclosed |
| US-3969526-A | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles | SMITHKLINE CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |
| US-3965113-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3962437-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3956499-A | ANTHELMINTICS | SMITHKLINE CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3935209-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-01-27 | — | — | US | disclosed |