SCHEMBL15516016

SCHEMBL15516016

CCc1cccc(NC(C)COC)c1C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
GAA P10253 1/20 0.41
ATM Q13315 1/20 0.41
ALDH1A1 P00352 4/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP2D6 P10635 1/20 0.39
HCAR3 P49019 2/20 0.39
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TP53 P04637 1/20 0.35
MAPK14 Q16539 1/20 0.35
NLRP3 Q96P20 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12674140 0.85 KDM4E (0.46) KDM4EMEN1KMT2AGAAATM
SCHEMBL11227410 0.80 MEN1 (0.44) KDM4EMEN1KMT2AGAAATM
SCHEMBL24635646 0.79 GABRA1 (0.33) KMT2AGAAALDH1A1CYP2D6NLRP3
SCHEMBL3466658 0.78 KDM4E (0.49) KDM4EMEN1KMT2AGAAATM
SCHEMBL30776762 0.78 KDM4E (0.49) KDM4EMEN1KMT2AGAAATM
SCHEMBL3466659 0.78 KDM4E (0.49) KDM4EMEN1KMT2AGAAATM
SCHEMBL5794071 0.78 KDM4E (0.49) KDM4EMEN1KMT2AGAAATM
SCHEMBL13626615 0.75 KDM4E (0.48) KDM4EATMALDH1A1CYP2D6HCAR3
SCHEMBL12674141 0.71 TAS1R3 (0.41) GAAALDH1A1SMN1; SMN2HSD17B10MAPK1
SCHEMBL11435587 0.71 KDM4E (0.39) KDM4EMEN1KMT2AGAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2892877-A1 PROCESS FOR THE PREPARATION OF (S)-2-ETHYL-N-(1-METHOXYPROPAN -2-YL)-6-METHYL ANILINE Council of Scientific and Industrial Research (IN) 2015-07-15 EP disclosed
WO-2014037962-A1 PROCESS FOR THE PREPARATION OF (S)-2-ETHYL-N-(1-METHOXYPROPAN -2-YL)-6-METHYL ANILINE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2014-03-13 WO disclosed