SCHEMBL1551682

SCHEMBL1551682

Cc1ccc(S(=O)(=O)ONC(N)=NN)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.50
PRSS1 P07477 3/20 0.50
PRSS2 P07478 3/20 0.50
PRSS3 P35030 3/20 0.50
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
CA12 O43570 1/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPT P10636 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1551834 0.84 CA2 (0.44) F2PRSS1PRSS2PRSS3CA1
SCHEMBL11794766 0.82 F2 (0.49) F2PRSS1PRSS2PRSS3CA1
SCHEMBL3179301 0.81 F2 (0.49) F2PRSS1PRSS2PRSS3CA1
SCHEMBL9247417 0.81 MAPT (0.48) F2PRSS1PRSS2PRSS3CA1
SCHEMBL973720 0.80 CA1 (0.47) F2PRSS1PRSS2PRSS3CA1
SCHEMBL4700990 0.79 CA9 (0.46) F2PRSS1PRSS2PRSS3CA1
SCHEMBL16897446 0.79 PKM (0.50) F2PRSS1PRSS2PRSS3CA1
SCHEMBL20085600 0.79 CA1 (0.46) F2PRSS1PRSS2PRSS3CA1
SCHEMBL28783036 0.77 SCN5A (0.49) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL8861762 0.76 ALDH1A1 (0.50) F2PRSS1PRSS2PRSS3CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9212402-B2 Aldehyde scrubbing in crust leather and tanned leather ROHM AND HAAS COMPANY (US) 2015-12-15 US disclosed
EP-2169080-B1 Aldehyde Scrubbing in Crust Leather and Tanned Leather ROHM & HAAS (US) 2011-04-27 EP disclosed
EP-2169080-A1 Aldehyde Scrubbing in Crust Leather and Tanned Leather Rohm and Haas Company (US) 2010-03-31 EP disclosed
US-20100068541-A1 Aldehyde scrubbing in crust leather and tanned leather ROHM AND HAAS COMPANY 2010-03-18 US disclosed
US-6991659-B2 Production of tanned leather and products suitable therefore CLARIANT FINANCE (BVI) LIMITED (VG) 2006-01-31 US disclosed
EP-1362128-B1 PRODUCTION OF TANNED LEATHER AND PRODUCTS SUITABLE THEREFORE CLARIANT FINANCE BVI LTD (VG) 2005-03-09 EP disclosed
US-20040074009-A1 Production of tanned leather and products suitable therefore CLARIANT FINANCE (BVI) LIMITED (VG) 2004-04-22 US disclosed
EP-1362128-A1 PRODUCTION OF TANNED LEATHER AND PRODUCTS SUITABLE THEREFORE Clariant Finance (BVI) Limited (VG) 2003-11-19 EP disclosed
US-6599943-B1 Preventive treatment, related to the radical generating nature of the xanthine dehydrogenase/xanthine oxidase WAPHARM AB (SE) 2003-07-29 US disclosed
WO-2002059382-A1 PRODUCTION OF TANNED LEATHER AND PRODUCTS SUITABLE THEREFORE CLARIANT INTERNATIONAL LTD (CH) 2002-08-01 WO disclosed
EP-1007025-A1 USE OF HYDROXYGUANIDINES Wa Pharm AB (SE) 2000-06-14 EP disclosed
WO-1998023267-A1 USE OF HYDROXYGUANIDINES WAPHARM AB (SE) 1998-06-04 WO disclosed
US-5108930-A Deprotenization of biological sample, reacting it with pyridine aldehyde to form pyridine aldehyde-substituted hydrazone of corresponding aminoguanidine; isolation, chromatographic analysis for quantity ALTEON INC. (US) 1992-04-28 US disclosed
EP-0448228-A2 Aminoguanidine assay and applications thereof ALTEON INC. (US) 1991-09-25 EP disclosed