SCHEMBL15517232

SCHEMBL15517232

COc1cc2c(cc1O)Oc1cc(O)c(OC)cc1C21OC(=O)c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.60
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
TDP1 Q9NUW8 4/20 0.60
FTO Q9C0B1 3/20 0.60
HTT P42858 2/20 0.60
CYP2C19 P33261 2/20 0.60
RECQL P46063 2/20 0.60
BLM P54132 2/20 0.60
PRMT1 Q99873 2/20 0.60
ACE2 Q9BYF1 2/20 0.60
HPGD P15428 1/20 0.60
SMAD3 P84022 1/20 0.60
LMNA P02545 6/20 0.55
USP2 O75604 2/20 0.55
ALDH1A1 P00352 2/20 0.55
CYP3A4 P08684 3/20 0.53
NPSR1 Q6W5P4 3/20 0.50
POLB P06746 2/20 0.50
GPR55 Q9Y2T6 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31620935 0.85 MAPT (0.71) MAPTMEN1KMT2ATDP1FTO
SCHEMBL7610486 0.83 HTT (0.46) MAPTMEN1KMT2ATDP1FTO
SCHEMBL10265071 0.83 PRMT1 (0.56) MAPTMEN1KMT2ATDP1FTO
SCHEMBL14750827 0.83 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO
SCHEMBL16181494 0.82 MAPT (0.53) MAPTMEN1KMT2ATDP1FTO
SCHEMBL13953177 0.82 MAPT (0.53) MAPTMEN1KMT2ATDP1FTO
SCHEMBL6407023 0.82 MAPT (0.53) MAPTMEN1KMT2ATDP1FTO
SCHEMBL4933751 0.82 MAPT (0.63) MAPTMEN1KMT2ATDP1FTO
SCHEMBL499135 0.80 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO
SCHEMBL499184 0.80 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106995493-A Catilan polypeptide and conjugate and its application 摩尔弗泰克有限公司 2017-08-01 CN disclosed
EP-3146337-A1 SUBSTRATE-MEDIATED REACTORS FOR BIOASSAYS Firefly Bioworks, Inc. (US) 2017-03-29 EP disclosed
WO-2015179848-A1 SUBSTRATE-MEDIATED REACTORS FOR BIOASSAYS FIREFLY BIOWORKS, INC. (US) 2015-11-26 WO disclosed
EP-2893035-A1 MULTIPLEX Y-STR ANALYSIS Life Technologies Corporation (US) 2015-07-15 EP disclosed
WO-2014039092-A1 MULTIPLEX Y-STR ANALYSIS Life Technologies Corporation (US) 2014-03-13 WO disclosed