SCHEMBL4933751

SCHEMBL4933751

CCc1cc2c(cc1O)Oc1cc(O)c(CC)cc1C21OC(=O)c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.63
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
TDP1 Q9NUW8 4/20 0.63
FTO Q9C0B1 4/20 0.63
HTT P42858 2/20 0.63
CYP2C19 P33261 2/20 0.63
RECQL P46063 2/20 0.63
BLM P54132 2/20 0.63
PRMT1 Q99873 2/20 0.63
ACE2 Q9BYF1 2/20 0.63
HPGD P15428 1/20 0.63
SMAD3 P84022 1/20 0.63
CYP3A4 P08684 3/20 0.58
LMNA P02545 6/20 0.57
USP2 O75604 2/20 0.57
ALDH1A1 P00352 2/20 0.57
NPSR1 Q6W5P4 3/20 0.52
POLB P06746 2/20 0.52
GPR55 Q9Y2T6 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4941419 0.91 MAPT (0.59) MAPTMEN1KMT2ATDP1FTO
SCHEMBL10176068 0.89 MAPT (0.54) MAPTMEN1KMT2ATDP1FTO
SCHEMBL31620935 0.87 MAPT (0.71) MAPTMEN1KMT2ATDP1FTO
SCHEMBL10176074 0.87 MAPT (0.54) MAPTMEN1KMT2ATDP1FTO
SCHEMBL4936913 0.86 MAPT (0.59) MAPTMEN1KMT2ATDP1FTO
SCHEMBL14750827 0.85 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO
SCHEMBL408340 0.85 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO
SCHEMBL30218785 0.85 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO
SCHEMBL29367262 0.85 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO
SCHEMBL22110661 0.85 FTO (0.72) MAPTMEN1KMT2ATDP1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080058524-A1 NOVEL DYES AND USE THEREOF IN THERMAL IMAGING MEMBERS AND METHODS ZINK IMAGING, LLC 2008-03-06 US disclosed
US-7279264-B2 Dyes and use thereof in thermal imaging members and methods ZINK IMAGING, LLC (US) 2007-10-09 US disclosed
US-20040204317-A1 Novel dyes and use thereof in imaging members and methods ZINK HOLDINGS LLC 2004-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040204317-A1 Novel dyes and use thereof in imaging members and methods ZKSCAN2, CACYBP, CDC73 MAPT 760/4885MEN1 2412/4885KMT2A 4649/4885
US-20080058524-A1 NOVEL DYES AND USE THEREOF IN THERMAL IMAGING MEMBERS AND METHODS CRYAB, CRYAA, ZKSCAN2 MAPT 371/4885MEN1 2732/4885KMT2A 4643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.