SCHEMBL7610486

SCHEMBL7610486

COc1cc2c(cc1O)Oc1cc(O)c(OC)cc1C21OC(=O)c2ccc(C(=O)O)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.46
FTO Q9C0B1 5/20 0.42
MAPT P10636 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HPGD P15428 2/20 0.42
RECQL P46063 2/20 0.42
CYP2C19 P33261 1/20 0.42
BLM P54132 1/20 0.42
SMAD3 P84022 1/20 0.42
PRMT1 Q99873 1/20 0.42
ACE2 Q9BYF1 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 4/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PKM P14618 2/20 0.41
GAA P10253 1/20 0.41
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4318993 0.84 FTO (0.43) HTTFTOMAPTMEN1KMT2A
SCHEMBL15517232 0.83 MAPT (0.60) HTTFTOMAPTMEN1KMT2A
SCHEMBL29613031 0.83 FTO (0.44) HTTFTOMAPTMEN1KMT2A
SCHEMBL4062067 0.83 FTO (0.44) HTTFTOMAPTMEN1KMT2A
SCHEMBL3656489 0.83 FTO (0.44) HTTFTOMAPTMEN1KMT2A
Bromide SCHEMBL23115511 0.82 FTO (0.43) HTTFTOMAPTMEN1KMT2A
SCHEMBL3685151 0.81 MEN1 (0.40) HTTFTOMAPTMEN1KMT2A
SCHEMBL2859711 0.80 FTO (0.42) HTTFTOMAPTMEN1KMT2A
SCHEMBL4921803 0.80 HTT (0.40) HTTMAPTMEN1KMT2ARECQL
SCHEMBL29353753 0.80 MEN1 (0.39) HTTMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6482938-B1 Compounds having energy transfer function and method for DNA base sequencing by using the same WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-19 US disclosed
EP-0967219-A1 COMPOUNDS HAVING ENERGY TRANSFER FUNCTION AND METHOD FOR DNA BASE SEQUENCING BY USING THE SAME THE INSTITUTE OF PHYSICAL & CHEMICAL RESEARCH (JP) 1999-12-29 EP disclosed