Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155179 | 1.00 | FASN (0.32) | FASNALDH1A1TSHRPTPN2PTPN1 | |
| SCHEMBL152497 | 0.81 | — | — | |
| SCHEMBL152496 | 0.81 | — | — | |
| SCHEMBL12373333 | 0.81 | — | — | |
| SCHEMBL731194 | 0.78 | ALDH1A1 (0.43) | FASNALDH1A1TSHRPTPN2PTPN1 | |
| SCHEMBL731193 | 0.78 | ALDH1A1 (0.43) | FASNALDH1A1TSHRPTPN2PTPN1 | |
| SCHEMBL28613509 | 0.77 | TRPA1 (0.38) | — | |
| SCHEMBL7290600 | 0.74 | PPARA (0.38) | FASNALDH1A1TSHRPTPN2PTPN1 | |
| SCHEMBL28569948 | 0.71 | ARG2 (0.34) | ALDH1A1 | |
| SCHEMBL12074100 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732102-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170002026-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-01-05 | — | — | US | disclosed |
| US-9328127-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-03 | — | — | US | disclosed |
| EP-2181103-B1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | UNIV ILLINOIS (US) | 2015-08-05 | — | — | EP | disclosed |
| US-20130296573-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-11-07 | — | — | US | disclosed |
| US-8318983-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120059184-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-03-08 | — | — | US | disclosed |
| US-8013203-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-09-06 | — | — | US | disclosed |
| EP-2181103-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | The Board Of Trustees Of The University Of Illinois (US) | 2010-05-05 | — | — | EP | disclosed |
| US-20090030238-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-29 | — | — | US | disclosed |
| WO-2009014550-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002026-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | FASN 2810/4885ALDH1A1 4216/4885TSHR 2658/4885 |
| US-20120059184-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | FASN 2810/4885ALDH1A1 4216/4885TSHR 2658/4885 |
| US-20130296573-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | FASN 2810/4885ALDH1A1 4216/4885TSHR 2658/4885 |
| US-20090030238-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | ORC3, BRS3, OSBPL3 | FASN 2810/4885ALDH1A1 4216/4885TSHR 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.