Phenol

Phenol

SCHEMBL15518162

CC1CC(=O)CC(C)(C)C1.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ALDH1A1 P00352 10/20 0.40
KMT2A Q03164 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
ALOX12 P18054 1/20 0.40
LMNA P02545 3/20 0.37
CYP3A4 P08684 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
KDM4E B2RXH2 3/20 0.36
MAPT P10636 4/20 0.36
MEN1 O00255 1/20 0.36
OPRM1 P35372 1/20 0.36
OPRD1 P41143 1/20 0.36
OPRK1 P41145 1/20 0.36
TDP1 Q9NUW8 3/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL21963466 1.00 ESR1 (0.41) ESR1ESR2ALDH1A1KMT2ANPSR1
Phenol SCHEMBL7159260 1.00 ESR1 (0.41) ESR1ESR2ALDH1A1KMT2ANPSR1
SCHEMBL24862 0.82 ALDH1A1 (0.42) ALDH1A1KMT2ANPSR1ALOX12LMNA
SCHEMBL4868570 0.82 ALDH1A1 (0.42) ALDH1A1KMT2ANPSR1ALOX12LMNA
SCHEMBL15411050 0.79 ESR1 (0.74) ESR1ESR2ALDH1A1SIGMAR1KDM4E
Phenol SCHEMBL11048957 0.75 MAPT (0.44) ALDH1A1KMT2ALMNACYP3A4CYP2C9
SCHEMBL3091142 0.73 LMNA (0.38) ALDH1A1KMT2ANPSR1ALOX12LMNA
SCHEMBL8677375 0.71 MAPT (0.53) ALDH1A1MAPT
SCHEMBL7102055 0.70 ESR2 (0.46) ESR1ESR2ALDH1A1KMT2ANPSR1
Phenol SCHEMBL8006872 0.70 TRPA1 (0.42) ESR1ESR2ALDH1A1ALOX12LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2891002-A1 METHODS OF MAKING AND ARTICLES COMPRISING A YELLOWING RESISTANT POLYCARBONATE COMPOSITION SABIC Global Technologies B.V. (NL) 2015-07-08 EP disclosed
WO-2014036254-A1 METHODS OF MAKING AND ARTICLES COMPRISING A YELLOWING RESISTANT POLYCARBONATE COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-03-06 WO disclosed