Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | KLK7 | P49862 | 6/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555040 | 0.82 | GPR119 (0.37) | GPR119KCNA3KDM4EPKM | |
| SCHEMBL4555170 | 0.77 | GPR119 (0.37) | KLK7GPR119RORCKLK5KDM4E | |
| SCHEMBL6481828 | 0.71 | KLK7 (0.37) | RIPK1KLK7GPR119RORCKLK5 | |
| SCHEMBL353105 | 0.71 | KLK7 (0.44) | RIPK1KLK7KLK5PRSS1PRSS2 | |
| SCHEMBL352415 | 0.69 | CHRM2 (0.35) | KLK7KDM4E | |
| SCHEMBL1149816 | 0.67 | RIPK1 (0.38) | RIPK1KLK7GPR119KLK5KDM4E | |
| SCHEMBL31526834 | 0.67 | RIPK1 (0.37) | RIPK1KLK7GPR119KLK5KDM4E | |
| SCHEMBL1149818 | 0.67 | RIPK1 (0.37) | RIPK1KLK7GPR119KLK5KDM4E | |
| SCHEMBL11917902 | 0.67 | CHRM2 (0.34) | RIPK1KDM4E | |
| SCHEMBL248353 | 0.66 | RIPK1 (0.61) | RIPK1KLK7GPR119RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094711-B1 | STRUCTURAL MIMETICS OF PROLINE-RICH PEPTIDES AND THE PHARMACEUTICAL USE THEREOF | FORSCHUNGSVERBUND BERLIN EV (DE) | 2014-03-19 | — | — | EP | disclosed |