Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 5/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053489 | 0.90 | TP53 (0.39) | TP53MAPTPPARGPPARAPPARD | |
| SCHEMBL14053267 | 0.84 | PPARG (0.39) | TP53MAPTPPARGPPARAPPARD | |
| SCHEMBL15520414 | 0.84 | NOD1 (0.38) | PPARGPPARAPPARDRORCHTR6 | |
| SCHEMBL15519365 | 0.84 | PPARG (0.41) | TP53MAPTPPARGPPARAPPARD | |
| SCHEMBL14054467 | 0.83 | PPARG (0.41) | TP53MAPTPPARGPPARAPPARD | |
| SCHEMBL14053482 | 0.81 | TP53 (0.42) | TP53MAPTPPARGPPARAPPARD | |
| SCHEMBL15519812 | 0.81 | TRPM8 (0.37) | TP53MAPTPPARGPPARAPPARD | |
| SCHEMBL14054162 | 0.81 | TP53 (0.38) | TP53MAPTPPARGPPARAPPARD | |
| SCHEMBL14053991 | 0.81 | TP53 (0.38) | TP53MAPTPPARGPPARAPPARD | |
| SCHEMBL14053616 | 0.80 | TP53 (0.42) | TP53MAPTPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |