Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18989874 | 0.73 | GDA (0.47) | KDM4EGDANOD1MAPTMAPK1 | |
| SCHEMBL3690781 | 0.72 | GDA (0.36) | GDANOD1MAPTDPP4BRDT | |
| SCHEMBL15519474 | 0.68 | DPP4 (0.40) | KDM4EMAPTMAPK1DPP4RECQL | |
| SCHEMBL23730754 | 0.66 | GDA (0.40) | KDM4EGDANOD1MAPTDPP4 | |
| SCHEMBL497538 | 0.65 | KDM4E (0.62) | KDM4EMAPTMAPK1RECQLMDM2 | |
| SCHEMBL30241271 | 0.64 | DPP4 (0.30) | NOD1DPP4 | |
| SCHEMBL9844556 | 0.64 | NOD1 (0.44) | KDM4EGDANOD1MAPK1DPP4 | |
| SCHEMBL3902925 | 0.63 | KDM4E (0.46) | KDM4EGDANOD1DPP4HPGD | |
| SCHEMBL9387992 | 0.62 | GDA (0.36) | GDANOD1DPP4BRDT | |
| SCHEMBL835443 | 0.62 | DPP4 (0.40) | GDANOD1DPP4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885302-B1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| US-9593119-B2 | Process for the preparation of dipeptidylpeptidase inhibitors | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2017-03-14 | — | — | US | disclosed |
| US-20160272642-A1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK LIFE SCIENCES LIMITED (IN) | 2016-09-22 | — | — | US | disclosed |
| US-9353114-B2 | Process for the preparation of dipeptidylpeptidase inhibitors | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-05-31 | — | — | US | disclosed |
| US-20150239887-A1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK GENERICS LIMITED (IN) | 2015-08-27 | — | — | US | disclosed |
| EP-2885302-A2 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | Glenmark Pharmaceuticals Limited (IN) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014033746-A2 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK PHARMACEUTICALS LIMITED; GLENMARK GENERICS LIMITED (IN) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239887-A1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | DPP4, DPP9, DPP3 | KDM4E 702/4885GDA 3792/4885NOD1 1540/4885 |
| US-20160272642-A1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | DPP9, DPP4, DPP7 | KDM4E 927/4885GDA 4417/4885NOD1 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.