Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18989874 | 0.77 | GDA (0.47) | GDAALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL21389576 | 0.73 | GDA (0.40) | GDAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27908390 | 0.68 | NOD1 (0.37) | GDAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL15519472 | 0.66 | KDM4E (0.38) | GDAALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL7004955 | 0.65 | GDA (0.49) | GDAALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL20097140 | 0.64 | GDA (0.62) | GDAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL22105384 | 0.64 | DPP4 (0.62) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL4037097 | 0.61 | GDA (0.41) | GDAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL1833932 | 0.60 | POLB (0.47) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL517356 | 0.59 | MAPT (0.46) | GDAMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397640-B1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INST NAT SANTE RECH MED (FR) | 2021-08-04 | — | — | EP | disclosed |