Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519604 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL15520936 | 0.75 | BCHE (0.40) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL15520940 | 0.65 | ALOX5AP (0.44) | SMN1; SMN2TP53MAPTALDH1A1GAA | |
| SCHEMBL834546 | 0.63 | CA1 (0.61) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL2680794 | 0.63 | HPGD (0.52) | SMN1; SMN2NPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL28330426 | 0.62 | RAB9A (0.56) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL15232928 | 0.62 | CA1 (0.52) | RAB9AALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL7995827 | 0.62 | CA1 (0.58) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL11650293 | 0.61 | CYP17A1 (0.59) | SMN1; SMN2LMNANPC1RAB9ACYP19A1 | |
| SCHEMBL31272944 | 0.61 | CNR1 (0.45) | SMN1; SMN2LMNAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014033497-A1 | 5-AZAINDOLE COMPOUNDS WITH ANTICANCER AND ANTIANGIOGENIC ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-06 | — | — | WO | disclosed |