Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | PDE1A | P54750 | 2/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15520936 | 0.82 | BCHE (0.40) | ALOX5APPDE1APDE1BPDE1CMAPT | |
| SCHEMBL15520900 | 0.77 | PLA2G2A (0.42) | MAPTTP53SMN1; SMN2P2RX4KMT2A | |
| SCHEMBL15519665 | 0.72 | RXFP1 (0.36) | MAPTKMT2AALDH1A1HTTMAPK1 | |
| SCHEMBL27899816 | 0.67 | P2RX4 (0.52) | MAPTTP53SMN1; SMN2P2RX4KMT2A | |
| SCHEMBL23270765 | 0.66 | ALOX5AP (0.52) | ALOX5APMAPTTP53PLA2G2A | |
| SCHEMBL30181242 | 0.66 | ALOX5AP (0.52) | ALOX5APMAPTTP53PLA2G2A | |
| SCHEMBL31000799 | 0.65 | NPBWR1 (0.50) | PDE1APDE1BPDE1CMAPTSMN1; SMN2 | |
| SCHEMBL3186354 | 0.65 | MAPK1 (0.51) | MAPTTP53SMN1; SMN2GAAKMT2A | |
| SCHEMBL25235955 | 0.65 | NPBWR1 (0.50) | PDE1APDE1BPDE1CMAPTSMN1; SMN2 | |
| SCHEMBL3470576 | 0.65 | CASR (0.76) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014033497-A1 | 5-AZAINDOLE COMPOUNDS WITH ANTICANCER AND ANTIANGIOGENIC ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-06 | — | — | WO | disclosed |