Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519665 | 0.85 | RXFP1 (0.36) | ALDH1A1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL15519664 | 0.85 | RXFP1 (0.36) | ALDH1A1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL15520940 | 0.82 | ALOX5AP (0.44) | ALDH1A1SMN1; SMN2TP53MAPTKMT2A | |
| SCHEMBL23479477 | 0.78 | RXFP1 (0.41) | LMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL15519603 | 0.75 | SMN1; SMN2 (0.35) | BCHEACHEDYRK1AMAOAALDH1A1 | |
| SCHEMBL15519604 | 0.75 | SMN1; SMN2 (0.35) | BCHEACHEDYRK1AMAOAALDH1A1 | |
| SCHEMBL15518815 | 0.72 | KDM4E (0.36) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL15520924 | 0.72 | BCHE (0.39) | BCHEACHEDYRK1AMAOAALDH1A1 | |
| SCHEMBL15521579 | 0.71 | DYRK1A (0.46) | BCHEACHEDYRK1AMAOAALDH1A1 | |
| SCHEMBL23474006 | 0.67 | CYP3A4 (0.48) | BCHEACHEDYRK1AMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014033497-A1 | 5-AZAINDOLE COMPOUNDS WITH ANTICANCER AND ANTIANGIOGENIC ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-06 | — | — | WO | disclosed |