Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 3/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 7/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 7/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 7/20 | 0.33 |
| ▸ | ATP1B2 | P14415 | 7/20 | 0.33 |
| ▸ | ATP1A2 | P50993 | 7/20 | 0.33 |
| ▸ | ATP1B3 | P54709 | 7/20 | 0.33 |
| ▸ | FXYD2 | P54710 | 7/20 | 0.33 |
| ▸ | ATP1A4 | Q13733 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23479477 | 0.83 | RXFP1 (0.41) | RXFP1BCL6LMNACYP3A4MAPT | |
| SCHEMBL16331628 | 0.75 | HPGD (0.50) | RXFP1ALDH1A1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL15520940 | 0.72 | ALOX5AP (0.44) | ALDH1A1HTTMAPTMAPK1KMT2A | |
| SCHEMBL23474006 | 0.72 | CYP3A4 (0.48) | RXFP1BCL6LMNACYP3A4MAPT | |
| SCHEMBL29196668 | 0.70 | RXFP1 (0.42) | RXFP1BCL6LMNACYP3A4MAPT | |
| SCHEMBL30855433 | 0.70 | RXFP1 (0.42) | RXFP1BCL6LMNACYP3A4MAPT | |
| SCHEMBL15518613 | 0.69 | ALDH1A1 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL23478503 | 0.68 | RXFP1 (0.41) | RXFP1BCL6LMNACYP3A4MAPT | |
| SCHEMBL16795077 | 0.68 | RXFP1 (0.41) | RXFP1BCL6LMNACYP3A4MAPT | |
| SCHEMBL16809631 | 0.67 | RHEB (0.46) | RXFP1ALDH1A1BCL6LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014033597-A1 | 5-AZAINDOLE COMPOUNDS WITH ANTICANCER AND ANTIANGIOGENIC ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-06 | — | — | WO | disclosed |
| WO-2014033497-A1 | 5-AZAINDOLE COMPOUNDS WITH ANTICANCER AND ANTIANGIOGENIC ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-06 | — | — | WO | disclosed |