Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12164169 | 0.80 | PDE3B (0.34) | PDE3BPDE3A | |
| SCHEMBL474031 | 0.80 | PDE3B (0.34) | PDE3BPDE3A | |
| SCHEMBL15520366 | 0.71 | CYP11B2 (0.44) | — | |
| SCHEMBL15520030 | 0.70 | PDE3B (0.33) | PDE3BPDE3A | |
| SCHEMBL2816563 | 0.65 | GPR55 (0.39) | PDE3BPDE3A | |
| SCHEMBL2817590 | 0.65 | GPR55 (0.39) | PDE3BPDE3A | |
| SCHEMBL474393 | 0.65 | GPR55 (0.39) | PDE3BPDE3A | |
| SCHEMBL12187874 | 0.65 | NR1H2 (0.30) | — | |
| SCHEMBL12164173 | 0.61 | CPT2 (0.36) | — | |
| SCHEMBL474367 | 0.61 | CPT2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411365-B1 | 2,3-DIARYL- OR HETEROARYL-SUBSTITUTED 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2014-03-19 | — | — | EP | disclosed |