Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519675 | 0.90 | TRPM8 (0.34) | MEN1GAAKMT2ATP53MAPT | |
| SCHEMBL15519975 | 0.90 | TP53 (0.39) | TP53MAPTTRPM8L3MBTL1KDM4E | |
| SCHEMBL14054353 | 0.85 | MAPT (0.37) | MEN1KMT2ATP53MAPTL3MBTL1 | |
| SCHEMBL15519812 | 0.82 | TRPM8 (0.37) | MEN1GAAKMT2ATP53MAPT | |
| SCHEMBL15519728 | 0.80 | TRPM8 (0.42) | TP53MAPTTRPM8L3MBTL1 | |
| SCHEMBL15519817 | 0.80 | TRPM8 (0.37) | TP53MAPTTRPM8KDM4EALDH1A1 | |
| SCHEMBL14053977 | 0.76 | CYP3A4 (0.36) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL12096891 | 0.75 | PPARG (0.45) | TP53MAPTACLYNPSR1RORC | |
| SCHEMBL14054035 | 0.75 | TRPM8 (0.44) | TRPM8RORC | |
| SCHEMBL15519981 | 0.75 | TRPM8 (0.36) | TP53TRPM8KDM4EALDH1A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |