Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 11/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053292 | 0.93 | PPARG (0.44) | PPARGPPARDPPARATRPM8NPC1 | |
| SCHEMBL15519780 | 0.86 | PPARG (0.42) | PPARGPPARDPPARATRPM8NPC1 | |
| SCHEMBL15520175 | 0.86 | PPARG (0.53) | PPARGPPARDPPARANPC1PKM | |
| SCHEMBL14053872 | 0.85 | CYP2C9 (0.42) | PPARGPPARDPPARANPC1PKM | |
| SCHEMBL15519262 | 0.80 | TRPM8 (0.43) | PPARGPPARDPPARATRPM8 | |
| SCHEMBL12096870 | 0.80 | PPARG (0.55) | PPARGPPARDPPARANPC1PKM | |
| SCHEMBL15519810 | 0.80 | TRPM8 (0.43) | PPARGPPARDPPARATRPM8RORC | |
| SCHEMBL27892484 | 0.79 | TRPM8 (0.34) | PPARGPPARDPPARATRPM8RORC | |
| SCHEMBL14053920 | 0.79 | PPARG (0.50) | PPARGPPARDPPARATRPM8NPC1 | |
| SCHEMBL15519980 | 0.78 | PPARG (0.40) | PPARGPPARDPPARATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |