Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 3/20 | 0.36 |
| ▸ | CPT1A | P50416 | 3/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053292 | 0.91 | PPARG (0.44) | PPARGPPARDPPARAKLKB1PKM | |
| SCHEMBL15520176 | 0.86 | PPARD (0.48) | PPARGPPARDPPARAKLKB1CPT2 | |
| SCHEMBL14053872 | 0.86 | CYP2C9 (0.42) | PPARGPPARDPPARAKLKB1PKM | |
| SCHEMBL15519779 | 0.86 | PPARG (0.47) | PPARGPPARDPPARAKLKB1PKM | |
| SCHEMBL15519263 | 0.81 | TRPM8 (0.38) | PPARGPPARDPPARATRPM8RORC | |
| SCHEMBL15519812 | 0.81 | TRPM8 (0.37) | PPARGPPARDPPARACPT2CPT1A | |
| SCHEMBL12096869 | 0.80 | PPARG (0.56) | PPARGPPARDPPARACPT2CPT1A | |
| SCHEMBL15519981 | 0.79 | TRPM8 (0.36) | PPARGPPARDPPARATRPM8RORC | |
| SCHEMBL12096687 | 0.79 | PPARG (0.54) | PPARGPPARDPPARACPT2CPT1A | |
| SCHEMBL12096870 | 0.78 | PPARG (0.55) | PPARGPPARDPPARAKLKB1CPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |