Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 14/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053670 | 0.93 | TRPM8 (0.40) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL15519262 | 0.91 | TRPM8 (0.43) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL15519810 | 0.88 | TRPM8 (0.43) | PPARGPPARAPPARDTRPM8PTGER2 | |
| SCHEMBL15519674 | 0.87 | TRPM8 (0.39) | PPARDTRPM8 | |
| SCHEMBL15519981 | 0.85 | TRPM8 (0.36) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL15519817 | 0.84 | TRPM8 (0.37) | TRPM8PTGER4 | |
| SCHEMBL14054203 | 0.84 | RORC (0.38) | PPARGPPARAPPARD | |
| SCHEMBL2279719 | 0.83 | TRPM8 (0.43) | TRPM8 | |
| SCHEMBL14054035 | 0.81 | TRPM8 (0.44) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL15519779 | 0.78 | PPARG (0.47) | PPARGPPARAPPARDTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |