Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PDE8B | O95263 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14729661 | 0.85 | RAB9A (0.40) | NPC1RAB9ASMN1; SMN2CD274RXRA | |
| SCHEMBL18483949 | 0.77 | CD274 (0.43) | NPC1RAB9ASMN1; SMN2CD274ATR | |
| SCHEMBL28361826 | 0.77 | CD274 (0.41) | CD274RXRARXRBRXRGCYP4F2 | |
| SCHEMBL25232393 | 0.76 | CD274 (0.40) | NPC1RAB9ASMN1; SMN2CD274RXRA | |
| SCHEMBL29586123 | 0.76 | CD274 (0.40) | NPC1RAB9ASMN1; SMN2CD274RXRA | |
| SCHEMBL18485036 | 0.76 | CD274 (0.40) | NPC1RAB9ASMN1; SMN2CD274RXRA | |
| SCHEMBL31338368 | 0.74 | RXRA (0.45) | NPC1RAB9ASMN1; SMN2CD274RXRA | |
| SCHEMBL15519361 | 0.74 | MEN1 (0.38) | CD274TSHR | |
| SCHEMBL21646747 | 0.74 | CD274 (0.41) | NPC1RAB9ASMN1; SMN2CD274RXRA | |
| SCHEMBL22381074 | 0.74 | CD274 (0.39) | NPC1RAB9ASMN1; SMN2CD274KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2708537-A1 | HETEROAROMATIC RING DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-03-19 | — | — | EP | disclosed |