Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.41 |
| ▸ | PPARD | Q03181 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2275980 | 0.92 | SMN1; SMN2 (0.41) | PPARGPPARAPPARDSMN1; SMN2NOD1 | |
| SCHEMBL15520419 | 0.86 | PPARG (0.41) | PPARGPPARAPPARDRXRARXRB | |
| SCHEMBL3531194 | 0.84 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL15520414 | 0.83 | NOD1 (0.38) | PPARGPPARAPPARDSMN1; SMN2NOD1 | |
| SCHEMBL15519365 | 0.83 | PPARG (0.41) | PPARGPPARAPPARDRORCRXRA | |
| SCHEMBL14054331 | 0.82 | IDH1 (0.43) | PPARGPPARAPPARDNOD1RORC | |
| SCHEMBL15519262 | 0.80 | TRPM8 (0.43) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL14054109 | 0.78 | RORC (0.39) | PPARGPPARAPPARDNOD1RORC | |
| SCHEMBL12096737 | 0.77 | PPARG (0.54) | PPARGPPARAPPARDRORC | |
| SCHEMBL14053489 | 0.75 | TP53 (0.39) | PPARGPPARAPPARDRORCIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |