SCHEMBL15522679

SCHEMBL15522679

[N-]=[N+]=NCc1nc2ccccc2c2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.53
APP P05067 2/20 0.41
GPR3 P46089 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
RAD52 P43351 1/20 0.36
MAOA P21397 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
GLA P06280 1/20 0.34
CHRM2 P08172 1/20 0.34
ADRA2A P08913 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
CHRM1 P11229 1/20 0.34
NQO2 P16083 1/20 0.34
DRD1 P21728 1/20 0.34
ACHE P22303 1/20 0.34
SLC6A2 P23975 1/20 0.34
CASP1 P29466 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28363563 0.87 KMT2A (0.41) KMT2AAPPGPR3SMN1; SMN2RAD52
SCHEMBL28363469 0.85 KMT2A (0.43) KMT2AAPPPOLBRAD52MAOA
SCHEMBL28883708 0.82 ESR1 (0.40) KMT2AAPP
SCHEMBL28359772 0.81 ELANE (0.37) KMT2AAPP
SCHEMBL28363542 0.80 ESR1 (0.38) KMT2AKDM4E
SCHEMBL28363448 0.77 BACE1 (0.35) KMT2AAPPPOLBALDH1A1HSD17B10
SCHEMBL28363465 0.77 ALDH1A1 (0.40) APPSMN1; SMN2POLBRAD52KDM4E
SCHEMBL16280692 0.73 ALDH1A1 (0.46) KMT2AAPPGPR3SMN1; SMN2POLB
SCHEMBL28669232 0.72 L3MBTL1 (0.37) KMT2AKDM4EALDH1A1NQO2KAT2B
SCHEMBL15692617 0.72 KDM4E (0.39) KMT2AAPPPOLBMAOAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110684989-A Method for electrochemically synthesizing 6-azido methyl phenanthridine compound 常州工学院 2020-01-14 CN claimed
CN-110714208-B Method for preparing 6- (sulfonyl methyl) phenanthridine compound through electrocatalysis 常州工学院 2020-12-29 CN disclosed
CN-110684989-B Method for electrochemically synthesizing 6-azido methyl phenanthridine compound 常州工学院 2020-08-04 CN disclosed
CN-110714208-A Method for preparing 6- (sulfonyl methyl) phenanthridine compound through electrocatalysis 常州工学院 2020-01-21 CN disclosed
CN-110684989-A Method for electrochemically synthesizing 6-azido methyl phenanthridine compound 常州工学院 2020-01-14 CN disclosed
US-9194802-B2 Luminescent probes having a phenanthridinyl antenna, and methods of use REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2015-11-24 US disclosed
US-9194802-B2 Luminescent probes having a phenanthridinyl antenna, and methods of use REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2015-11-24 US disclosed
US-20140080163-A1 LUMINESCENT PROBES HAVING A PHENANTHRIDINYL ANTENNA, AND METHODS OF USE NATIONAL SCIENCE FOUNDATION 2014-03-20 US disclosed
US-20140080163-A1 LUMINESCENT PROBES HAVING A PHENANTHRIDINYL ANTENNA, AND METHODS OF USE NATIONAL SCIENCE FOUNDATION 2014-03-20 US disclosed