Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882899 | 0.89 | CYP3A4 (0.36) | CYP3A4 | |
| SCHEMBL468846 | 0.89 | CYP3A4 (0.36) | CYP3A4 | |
| SCHEMBL15756820 | 0.75 | DPP4 (0.38) | — | |
| SCHEMBL1966761 | 0.74 | — | — | |
| SCHEMBL8185651 | 0.72 | — | — | |
| SCHEMBL2544911 | 0.70 | OPRM1 (0.34) | — | |
| SCHEMBL3214466 | 0.69 | DPP4 (0.42) | — | |
| SCHEMBL1966290 | 0.69 | CYP2C19 (0.30) | CYP2C19 | |
| SCHEMBL1991499 | 0.68 | JAK3 (0.32) | — | |
| SCHEMBL10484687 | 0.68 | L3MBTL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9283191-B2 | Compressed chewing gum tablet | FERTIN PHARMA A/S (DK) | 2016-03-15 | — | — | US | disclosed |
| US-20140079756-A1 | Compressed Chewing Gum Tablet | FERTIN PHARMA A/S (DK) | 2014-03-20 | — | — | US | disclosed |