SCHEMBL155229

SCHEMBL155229

CCCCCC=CCC=CCCCCCCCCOS(C)(=O)=O

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.53
KDM4E B2RXH2 1/20 0.52
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
MMP9 P14780 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
TRPV1 Q8NER1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL152161 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL14889921 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL29670877 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL14890072 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL8836139 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL14890074 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL155228 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL14889920 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL8836145 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA
SCHEMBL25869247 1.00 FAAH (0.53) FAAHKDM4EUSP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4495237-B1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORP (CA) 2026-05-13 EP disclosed
EP-4036079-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-11-19 EP disclosed
EP-3275448-B1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES KYOWA KIRIN CO LTD (JP) 2025-10-29 EP disclosed
US-12453776-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2025-10-28 US disclosed
EP-3456317-B1 DI-ALIPHATIC SUBSTITUTED PEGYLATED LIPIDS ALNYLAM PHARMACEUTICALS INC (US) 2025-09-24 EP disclosed
US-12396961-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2025-08-26 US disclosed
EP-3394030-B2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-02-12 EP disclosed
EP-4495237-A2 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS Arbutus Biopharma Corporation (CA) 2025-01-22 EP disclosed
US-20240424105-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-12-26 US disclosed
EP-4241767-B1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORP (CA) 2024-10-23 EP disclosed
WO-2009132131-A1 AMINO LIPID BASED IMPROVED LIPID FORMULATION ALNYLAM PHARMACEUTICALS, INC. (US) 2009-10-29 WO disclosed
WO-2009129385-A1 CATIONIC LIPIDS AND USES THEREOF ABBOTT LABORATORIES (US) 2009-10-22 WO disclosed
WO-2009129387-A2 CATIONIC LIPIDS AND USES THEREOF ABBOTT LABORATORIES (US) 2009-10-22 WO disclosed
WO-2009129395-A1 CATIONIC LIPIDS AND USES THEREOF ABBOTT LABORATORIES (US) 2009-10-22 WO disclosed
US-7514099-B2 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules SIRNA THERAPEUTICS, INC. (US) 2009-04-07 US disclosed
US-20090048197-A1 Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules SIRNA THERAPEUTICS, INC. (US) 2009-02-19 US disclosed
US-20080188675-A1 LIPID NANOPARTICLE BASED COMPOSITIONS AND METHODS FOR THE DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES SIRNA THERAPEUTICS INC. (US) 2008-08-07 US disclosed
US-7404969-B2 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules SIRNA THERAPEUTICS, INC. (US) 2008-07-29 US disclosed
US-20080020058-A1 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules SIRNA THERAPEUTICS, INC. (US) 2008-01-24 US disclosed
US-20060240554-A1 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules SIRNA THERAPEUTICS, INC. (US) 2006-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048197-A1 Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules PHAX, CETP, LIPC FAAH 1505/4885KDM4E 3974/4885USP2 4413/4885
US-12453776-B2 Lipids and compositions for the delivery of therapeutics PHOSPHO1, MBOAT1, SGMS1 FAAH 550/4885KDM4E 1867/4885USP2 3230/4885
US-20060240554-A1 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules PHAX, CETP, LIPC FAAH 1624/4885KDM4E 3996/4885USP2 4357/4885
US-20240424105-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS PHOSPHO1, MBOAT1, SGMS1 FAAH 503/4885KDM4E 1963/4885USP2 3127/4885
US-12396961-B2 Compounds and compositions for intracellular delivery of agents LNPK, PLTP, PHOSPHO1 FAAH 3097/4885KDM4E 4340/4885USP2 1288/4885
US-20080020058-A1 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules PHAX, CETP, LIPC FAAH 1505/4885KDM4E 3974/4885USP2 4413/4885
US-20080188675-A1 LIPID NANOPARTICLE BASED COMPOSITIONS AND METHODS FOR THE DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES PHAX, CETP, LIPC FAAH 1624/4885KDM4E 3996/4885USP2 4357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.