SCHEMBL15524203

SCHEMBL15524203

C=Cc1ccc(Br)c(CCCl)c1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15524523 0.85 ALDH1A1 (0.36) ALDH1A1TP53TDP1TRPA1
SCHEMBL809841 0.85 ALDH1A1 (0.39) ALDH1A1TP53TDP1TSHRTRPA1
SCHEMBL15524463 0.83 ALDH1A1 (0.37) ALDH1A1TP53TDP1TRPA1
SCHEMBL810266 0.79 ALDH1A1 (0.37) ALDH1A1TP53TDP1TRPA1
SCHEMBL15524310 0.79 ALDH1A1 (0.40) ALDH1A1TP53TDP1TSHRTRPA1
SCHEMBL809920 0.78 TP53 (0.38) ALDH1A1TP53TDP1TRPA1
SCHEMBL14761059 0.78 TRPA1 (0.44) ALDH1A1CYP2C19TRPA1
SCHEMBL25370539 0.77 ALDH1A1 (0.39) ALDH1A1TP53TDP1CYP2D6TSHR
SCHEMBL16960986 0.77 ALDH1A1 (0.39) ALDH1A1TP53TDP1TSHRTRPA1
SCHEMBL10748244 0.74 HSP90AA1 (0.38) ALDH1A1TDP1CYP1A2CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed