SCHEMBL15524310

SCHEMBL15524310

C=Cc1ccc(Br)c(CBr)c1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TRPA1 O75762 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15524463 0.84 ALDH1A1 (0.37) ALDH1A1TP53TDP1TRPA1
SCHEMBL15524634 0.83 ALDH1A1 (0.40) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL25370539 0.82 ALDH1A1 (0.39) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL809841 0.82 ALDH1A1 (0.39) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL16960986 0.82 ALDH1A1 (0.39) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL15524203 0.79 ALDH1A1 (0.36) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL15524685 0.78 TRPA1 (0.47) ALDH1A1TRPA1
SCHEMBL2788648 0.75 ALDH1A1 (0.50) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL15524799 0.73 TP53 (0.41) ALDH1A1TP53TDP1TRPA1TSHR
SCHEMBL15524811 0.73 ALDH1A1 (0.39) ALDH1A1TP53TDP1TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed