Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884437 | 0.94 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL3951427 | 0.86 | TSHR (0.40) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Acrylic Acid SCHEMBL5820204 | 0.85 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL35807 | 0.85 | TSHR (0.51) | TSHRHPGDALDH1A1THRBPOLB | |
| SCHEMBL333002 | 0.84 | TSHR (0.50) | TSHRHPGDALDH1A1THRBPOLB | |
| SCHEMBL331043 | 0.84 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL4883019 | 0.83 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL8212857 | 0.82 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL395328 | 0.82 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL9309438 | 0.82 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2112179-B1 | Surface-treated powders, and cosmetics comprising the same | SHISEIDO CO LTD (JP) | 2011-04-27 | — | — | EP | disclosed |
| EP-1803750-B1 | USE OF A POLYMER FOR SURFACE-TREATING A POWDER | SHISEIDO CO LTD (JP) | 2009-12-09 | — | — | EP | disclosed |
| EP-2112179-A1 | Surface-treated powders, and cosmetics comprising the same | Shiseido Co., Ltd. (JP) | 2009-10-28 | — | — | EP | disclosed |
| EP-1803750-A1 | SURFACE-TREATING AGENT, SURFACE-TREATED POWDER, AND COSMETIC PREPARATION CONTAINING SAME | Shiseido Company, Limited (JP) | 2007-07-04 | — | — | EP | disclosed |