SCHEMBL15524879

SCHEMBL15524879

CC(C)CCCc1cc(O)cc(C(=O)O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PTPN1 P18031 5/20 0.37
HMGB1 P09429 3/20 0.37
PTPN11 Q06124 2/20 0.37
PTPN2 P17706 3/20 0.36
PTPN6 P29350 2/20 0.36
GPR84 Q9NQS5 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
CXCL12 P48061 2/20 0.36
ALOX5 P09917 5/20 0.36
PTGS2 P35354 3/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15524690 0.95 ALDH1A1 (0.38) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1
SCHEMBL13835362 0.94 ALOX5 (0.39) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1
SCHEMBL9500669 0.86 GRIN2D (0.47) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1
SCHEMBL9700901 0.85 GRIN2D (0.46) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1
SCHEMBL9502083 0.82 AKR1C2 (0.38) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1
SCHEMBL39883 0.82 GABRP (0.49) ALDH1A1HPGDHSD17B10PTPN1PTPN11
SCHEMBL9504239 0.81 AKR1C2 (0.45) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1
SCHEMBL25400262 0.81 GRIN2D (0.48) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1
SCHEMBL8916836 0.81 HMGB1 (0.36) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1
SCHEMBL3776599 0.81 KAT8 (0.43) GRIN2DGRIN2AGRIN2BGRIN2CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed