Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.49 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | ABHD11 | Q8NFV4 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118446 | 0.82 | SLC6A11 (0.55) | SLC6A1SLC6A11FFAR1CYP3A4MEN1 | |
| SCHEMBL764125 | 0.79 | SLC6A11 (0.52) | SLC6A1SLC6A11FFAR1CYP3A4MEN1 | |
| SCHEMBL4140738 | 0.78 | ABHD6 (0.54) | DAGLAABHD6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL15811746 | 0.78 | ABHD6 (0.54) | DAGLAABHD6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL26502803 | 0.77 | SLC6A11 (0.52) | SLC6A1DAGLAABHD6SLC6A11FFAR1 | |
| SCHEMBL27138500 | 0.77 | RIPK1 (0.40) | SLC6A1SLC6A11MEN1KMT2ARIPK1 | |
| SCHEMBL19617254 | 0.76 | ABHD6 (0.56) | DAGLAABHD6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL15811762 | 0.76 | ABHD6 (0.56) | DAGLAABHD6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL6360197 | 0.76 | ABHD6 (0.56) | DAGLAABHD6CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL5413716 | 0.75 | FFAR1 (0.55) | DAGLAABHD6CHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838535-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE | Biocryst Pharmaceuticals, Inc. (US) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013158746-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE | BIOCRYST PHARMACEUTICALS, INC. (US) | 2013-10-24 | — | — | WO | disclosed |