Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 9/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15526258 | 0.86 | LIPE (0.45) | LIPECXCR2HDAC2 | |
| SCHEMBL15607766 | 0.86 | LIPE (0.43) | LIPECXCR2HDAC2FASN | |
| SCHEMBL3705786 | 0.73 | LIPE (0.42) | LIPEHDAC2 | |
| SCHEMBL15607794 | 0.72 | HDAC1 (0.44) | LIPEHDAC2 | |
| SCHEMBL29709592 | 0.72 | HDAC1 (0.44) | LIPEHDAC2 | |
| SCHEMBL15607774 | 0.70 | MAPT (0.43) | HDAC2FASN | |
| SCHEMBL31703994 | 0.69 | KDR (0.44) | HDAC2FASN | |
| SCHEMBL28643584 | 0.69 | NPC1 (0.46) | LIPEHDAC2 | |
| SCHEMBL12650248 | 0.68 | LIPE (0.42) | LIPEHDAC2 | |
| SCHEMBL28793298 | 0.67 | LIPE (0.52) | LIPECXCR2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013157021-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2013-10-24 | — | — | WO | disclosed |