Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 9/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705786 | 0.88 | LIPE (0.42) | LIPEHDAC2 | |
| SCHEMBL15525965 | 0.86 | LIPE (0.46) | LIPECXCR2HDAC2 | |
| SCHEMBL15607766 | 0.84 | LIPE (0.43) | LIPECXCR2GABRA1HDAC2PDE10A | |
| SCHEMBL16343945 | 0.83 | LIPE (0.47) | LIPE | |
| SCHEMBL15956659 | 0.82 | LIPE (0.43) | LIPECXCR2 | |
| SCHEMBL15956897 | 0.81 | LIPE (0.43) | LIPEHDAC2 | |
| SCHEMBL3720444 | 0.81 | LIPE (0.46) | LIPECXCR2 | |
| SCHEMBL3872642 | 0.81 | LIPE (0.44) | LIPECXCR2 | |
| SCHEMBL15957110 | 0.78 | LIPE (0.45) | LIPECXCR2 | |
| SCHEMBL106631 | 0.74 | TAS1R3 (0.39) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013157021-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2013-10-24 | — | — | WO | disclosed |