SCHEMBL15526587

SCHEMBL15526587

CC(C)[Si](Cl)(C(C)C)[Si](Cl)(C(C)C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8419591 0.82
SCHEMBL8421393 0.79
SCHEMBL705202 0.74
SCHEMBL8420011 0.73
SCHEMBL524075 0.70
SCHEMBL297953 0.70
SCHEMBL37015 0.70 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL523409 0.70
SCHEMBL8420283 0.70 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL11240395 0.67 ALDH1A1 (0.40) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841401-B1 METHOD FOR PROTECTING HYDROXYL, AMINE OR THIOL FUNCTIONAL GROUPS WITH TETRAISOPROPYLDISILANE AND THE CORRESPONDING PROTECTED COMPOUNDS INST CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) 2018-07-04 EP disclosed
US-9290521-B2 Method for protecting hydroxyl or amine or thiol functions, novel compounds with protected hydroxyl or amine or thiol groups, as well novel compounds for the implementation of this method INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) 2016-03-22 US disclosed
US-20150094462-A1 METHOD FOR PROTECTING HYDROXYL OR AMINE OR THIOL FUNCTIONS, NOVEL COMPOUNDS WITH PROTECTED HYDROXYL OR AMINE OR THIOL GROUPS, AS WELL NOVEL COMPOUNDS FOR THE IMPLEMENTATION OF THIS METHOD FUNDACJA UNIWERSYTETU IM. ADAMA MICKIEWICZA W POZNANIU (PL) 2015-04-02 US disclosed
EP-2841401-A1 METHOD FOR PROTECTING HYDROXYL, AMINE OR THIOL FUNCTIONAL GROUPS WITH TETRAISOPROPYDISILANE AND THE CORRESPONDING PROTECTED COMPOUNDS Instytut Chemii Bioorganicznej Polskiej Akademii Nauk (PL) 2015-03-04 EP disclosed
WO-2013165266-A1 METHOD FOR PROTECTING HYDROXYL, AMINE OR THIOL FUNCTIONAL GROUPS WITH TETRAISOPROPYDISILANE AND THE CORRESPONDING PROTECTED COMPOUNDS INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) 2013-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150094462-A1 METHOD FOR PROTECTING HYDROXYL OR AMINE OR THIOL FUNCTIONS, NOVEL COMPOUNDS WITH PROTECTED HYDROXYL OR AMINE OR THIOL GROUPS, AS WELL NOVEL COMPOUNDS FOR THE IMPLEMENTATION OF THIS METHOD DUS2, TXN, OGG1 ALDH1A1 388/4885TSHR 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.