Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.78 |
| ▸ | RXRA | P19793 | 1/20 | 0.78 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.78 |
| ▸ | CDK2 | P24941 | 1/20 | 0.78 |
| ▸ | RXRB | P28702 | 1/20 | 0.78 |
| ▸ | RXRG | P48443 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | SOD1 | P00441 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Dehydroabietate SCHEMBL32671489 | 1.00 | KARS1 (0.78) | KARS1RXRACCNE1CDK2RXRB | |
| Methyl Dehydroabietate SCHEMBL2603428 | 1.00 | KARS1 (0.78) | KARS1RXRACCNE1CDK2RXRB | |
| Methyl Dehydroabietate SCHEMBL2603432 | 1.00 | KARS1 (0.78) | KARS1RXRACCNE1CDK2RXRB | |
| Methyl Dehydroabietate SCHEMBL30128305 | 1.00 | KARS1 (0.78) | KARS1RXRACCNE1CDK2RXRB | |
| Methyl Dehydroabietate SCHEMBL932871 | 1.00 | KARS1 (0.78) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL15342390 | 0.91 | SOD1 (0.70) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL20082366 | 0.90 | CYP3A4 (0.78) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL2606230 | 0.90 | KARS1 (0.77) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL8664055 | 0.89 | KARS1 (0.74) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL2603429 | 0.89 | KARS1 (0.74) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114426507-B | Method for synthesizing methyl thiomethylene ester compound | 南京师范大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114426507-A | Synthetic method of methyl-thiomethylene ester compound | 南京师范大学 | 2022-05-03 | — | — | CN | disclosed |
| WO-2013166406-A1 | METHODS OF DISTINGUISHING BETWEEN SIMILAR COMPOSITIONS | BATTELLE MEMORIAL INSTITUTE (US) | 2013-11-07 | — | — | WO | disclosed |