Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | KARS1 | Q15046 | 4/20 | 0.77 |
| ▸ | RXRA | P19793 | 1/20 | 0.77 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.77 |
| ▸ | CDK2 | P24941 | 1/20 | 0.77 |
| ▸ | RXRB | P28702 | 1/20 | 0.77 |
| ▸ | RXRG | P48443 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.62 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.62 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.62 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | SOD1 | P00441 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Dehydroabietate SCHEMBL15526779 | 0.90 | KARS1 (0.78) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Methyl Dehydroabietate SCHEMBL30128305 | 0.90 | KARS1 (0.78) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Methyl Dehydroabietate SCHEMBL2603428 | 0.90 | KARS1 (0.78) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Methyl Dehydroabietate SCHEMBL932871 | 0.90 | KARS1 (0.78) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Methyl Dehydroabietate SCHEMBL2603432 | 0.90 | KARS1 (0.78) | CYP3A4LMNAKARS1RXRACCNE1 | |
| Methyl Dehydroabietate SCHEMBL32671489 | 0.90 | KARS1 (0.78) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL2606230 | 0.89 | KARS1 (0.77) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL2989705 | 0.88 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL3462324 | 0.88 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 | |
| SCHEMBL30383762 | 0.88 | CYP3A4 (1.00) | CYP3A4LMNAKARS1RXRACCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578620-B1 | RESIN-ADDITIVE MASTERBATCH | ADEKA CORP (JP) | 2018-04-25 | — | — | EP | disclosed |