Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 6/20 | 0.36 |
| ▸ | CES1 | P23141 | 6/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15527616 | 0.86 | CES2 (0.42) | CES2CES1PTGS2 | |
| SCHEMBL15364154 | 0.84 | CES2 (0.38) | CES2CES1ATMLMNAPTGS2 | |
| SCHEMBL15527470 | 0.84 | KDM1A (0.39) | KDM1ACES2CES1ATMLMNA | |
| SCHEMBL15527450 | 0.73 | KDM1A (0.42) | KDM1ACES2CES1DEGS1AKT1 | |
| SCHEMBL15364808 | 0.70 | CES2 (0.45) | CES2CES1PTGS2 | |
| SCHEMBL15364144 | 0.70 | CES2 (0.45) | CES2CES1PTGS2 | |
| SCHEMBL30705332 | 0.70 | KDM1A (0.44) | KDM1ACES2CES1MTNR1AMTNR1B | |
| SCHEMBL15527332 | 0.69 | KDM1A (0.40) | KDM1ACES2CES1DEGS1ESR1 | |
| SCHEMBL10907609 | 0.69 | CYP1A2 (0.42) | KDM1ACES2CES1ATMLMNA | |
| SCHEMBL9757698 | 0.69 | CYP1A2 (0.42) | KDM1ACES2CES1ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844678-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | Bridgestone Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013166124-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | WO | disclosed |