Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 7/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 6/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364808 | 0.86 | CES2 (0.45) | CES2CES1NAAAPTGS2TDP1 | |
| SCHEMBL15364144 | 0.86 | CES2 (0.45) | CES2CES1NAAAPTGS2TDP1 | |
| SCHEMBL15527231 | 0.86 | KDM1A (0.37) | CES2CES1PTGS2 | |
| SCHEMBL15527470 | 0.78 | KDM1A (0.39) | CES2CES1 | |
| SCHEMBL16167155 | 0.74 | TBXAS1 (0.47) | CES2CES1NAAAPTGS2TDP1 | |
| SCHEMBL16167208 | 0.74 | TBXAS1 (0.47) | CES2CES1NAAAPTGS2TDP1 | |
| SCHEMBL16167375 | 0.74 | TBXAS1 (0.47) | CES2CES1NAAAPTGS2TDP1 | |
| SCHEMBL16167374 | 0.74 | TBXAS1 (0.47) | CES2CES1NAAAPTGS2TDP1 | |
| SCHEMBL16167083 | 0.74 | TBXAS1 (0.47) | CES2CES1NAAAPTGS2TDP1 | |
| SCHEMBL16167372 | 0.74 | TBXAS1 (0.47) | CES2CES1NAAAPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844678-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | Bridgestone Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013166124-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | WO | disclosed |