Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.75 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.75 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589726 | 1.00 | PARP1 (0.75) | PARP1PARP15PARP10MEN1KMT2A | |
| SCHEMBL8787974 | 0.85 | ALDH1A1 (0.64) | PARP1PARP15PARP10MEN1KMT2A | |
| SCHEMBL8787978 | 0.85 | ALDH1A1 (0.64) | PARP1PARP15PARP10MEN1KMT2A | |
| SCHEMBL8787970 | 0.85 | ALDH1A1 (0.64) | PARP1PARP15PARP10MEN1KMT2A | |
| SCHEMBL8468337 | 0.83 | MAPT (0.61) | PARP1PARP15PARP10MEN1KMT2A | |
| Zinc Ion SCHEMBL7937241 | 0.83 | MEN1 (0.55) | PARP1PARP15PARP10MEN1KMT2A | |
| SCHEMBL8468336 | 0.83 | MAPT (0.61) | PARP1PARP15PARP10MEN1KMT2A | |
| Zinc Ion SCHEMBL7937239 | 0.83 | MEN1 (0.55) | PARP1PARP15PARP10MEN1KMT2A | |
| SCHEMBL11051647 | 0.80 | MEN1 (0.60) | PARP1PARP15PARP10MEN1KMT2A | |
| SCHEMBL11759294 | 0.79 | MEN1 (0.58) | PARP1PARP15PARP10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119573-B1 | Functionalized elastomers | GOODYEAR TIRE & RUBBER (US) | 2011-04-27 | — | — | EP | claimed |
| JP-10087589-A | — | — | None | — | — | JP | disclosed |
| US-20020174926-A1 | Tire with rubber sidewall insert which contains an aryl citraconamic acid in the insert rubber composition | D SIDOCKY RICHARD MICHAEL (US) | 2002-11-28 | — | — | US | disclosed |
| EP-1241212-A2 | Tire with rubber sidewall insert which contains aryl citraconamic acid in the insert rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-09-18 | — | — | EP | disclosed |
| EP-0823417-B1 | Zinc salts of citraconamic acid and rubber compounds containing such salts | GOODYEAR TIRE & RUBBER (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0823452-B1 | Rubber compounds containing aryl bis citraconamic acids | GOODYEAR TIRE & RUBBER (US) | 1999-12-08 | — | — | EP | disclosed |
| JP-H1087589-A | ZINC CITRACONAMIDATE AND RUBBER COMPOUND CONTAINING SALT LIKE THE SAME | GOODYEAR TIRE & RUBBER CO:THE | 1998-04-07 | — | — | JP | disclosed |
| US-5728757-A | FOR USE IN TIRES, POWER BELTS, CONVEYOR BELTS, RUBBER WRINGERS, AUTOMOBILE FLOOR MATS, MUD FLAPS AND BALL MILL LINERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0823452-A1 | Rubber compounds containing aryl bis citraconamic acids | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-02-11 | — | — | EP | disclosed |
| EP-0823417-A1 | Zinc salts of citraconamic acid and rubber compounds containing such salts | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-02-11 | — | — | EP | disclosed |
| US-5696188-A | Rubber compounds containing aryl bis citraconamic acids | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-12-09 | — | — | US | disclosed |