Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 7/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.59 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666505 | 0.87 | NAPRT (0.55) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL8263524 | 0.87 | NAPRT (0.55) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL7589726 | 0.80 | PARP1 (0.75) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL1552733 | 0.80 | PARP1 (0.75) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL11759294 | 0.80 | MEN1 (0.58) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL9312293 | 0.80 | MEN1 (0.73) | MEN1KMT2ALPAR1LPAR2ALDH1A1 | |
| SCHEMBL23918242 | 0.78 | DDAH1 (0.64) | ALDH1A1MAPTPOLBRAB9ALMNA | |
| SCHEMBL11048872 | 0.78 | DEGS1 (0.61) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| Zinc Ion SCHEMBL7937239 | 0.77 | MEN1 (0.55) | MEN1KMT2APARP1PARP10PARP15 | |
| Zinc Ion SCHEMBL7937241 | 0.77 | MEN1 (0.55) | MEN1KMT2APARP1PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424336-A | Meat-curable mixture, which are stable on storage, of epoxide resin, 3-aminocrotonic acid derivatives and maleimide compound | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| US-4360655-A | Heat-curable mixtures, which are stable on storage, of epoxide compounds β-aminocrotonic acid derivatives and polyamine | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4348511-A | POLYURETHANES MODIFIED WITH BETA-AMINOCROTONIC ACID DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| US-4291146-A | Heat-curable mixtures, which are stable on storage, of expoxide resins and β-aminocrotonic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |
| US-4284752-A | Process for producing crosslinked unsaturated polymers by reaction of .beta. | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| US-4161580-A | Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-4089845-A | Thermosetting mixtures which are stable on storage from polyimide and .beta. | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |