Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 18/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL449419 | 0.91 | ALDH1A1 (0.50) | CXCR3PRSS1ALDH1A1 | |
| SCHEMBL454538 | 0.91 | CXCR3 (0.47) | CXCR3PRSS1 | |
| SCHEMBL451971 | 0.91 | CXCR3 (0.47) | CXCR3PRSS1 | |
| SCHEMBL454416 | 0.89 | CXCR3 (0.48) | CXCR3PRSS1 | |
| SCHEMBL451511 | 0.89 | PRSS1 (0.49) | CXCR3PRSS1 | |
| SCHEMBL451205 | 0.88 | CXCR3 (0.50) | CXCR3PRSS1ALDH1A1 | |
| SCHEMBL451506 | 0.88 | CXCR3 (0.46) | CXCR3PRSS1ALDH1A1 | |
| SCHEMBL452826 | 0.88 | POLB (0.50) | CXCR3PRSS1ALDH1A1 | |
| SCHEMBL448755 | 0.88 | PRSS1 (0.43) | CXCR3PRSS1 | |
| SCHEMBL453544 | 0.88 | HTR6 (0.46) | CXCR3PRSS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521746-B1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2011-04-27 | — | — | EP | claimed |