Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247811 | 0.84 | HDAC1 (0.65) | HDAC1HDAC6THRBLMNAHIF1A | |
| SCHEMBL2998853 | 0.83 | HDAC1 (0.59) | HDAC1HDAC6THRBLMNAHIF1A | |
| SCHEMBL3248999 | 0.82 | HDAC1 (0.62) | HDAC1HDAC6THRBLMNAHIF1A | |
| SCHEMBL2224455 | 0.79 | HDAC1 (0.69) | HDAC1HDAC6THRBLMNAHIF1A | |
| SCHEMBL7530416 | 0.79 | HDAC1 (0.59) | HDAC1HDAC6THRBLMNAHIF1A | |
| SCHEMBL2000041 | 0.79 | HDAC1 (0.74) | HDAC1HDAC6THRBLMNAHIF1A | |
| SCHEMBL5361880 | 0.79 | HDAC1 (0.74) | HDAC1HDAC6THRBLMNAHIF1A | |
| SCHEMBL997166 | 0.78 | GAA (0.72) | HDAC1HDAC6THRBLMNAHIF1A | |
| Nicoxamat SCHEMBL93839 | 0.77 | HDAC1 (1.00) | HDAC1HDAC6THRBLMNAHIF1A | |
| SCHEMBL28954991 | 0.77 | SMN1; SMN2 (0.59) | HDAC1HDAC6GAAALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117026626-A | Carbon fiber core copper wire and preparation method thereof | 江苏集萃碳纤维及复合材料应用技术研究院有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-115142148-B | High-performance binary polyacrylonitrile-based carbon fiber precursor and preparation method thereof | 东华大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115142148-A | High-performance binary polyacrylonitrile-based carbon fiber precursor and preparation method thereof | 东华大学 | 2022-10-04 | — | — | CN | claimed |
| US-10125118-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2018-11-13 | — | — | US | claimed |
| US-20170355690-A9 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-12-14 | — | — | US | claimed |
| US-20170066742-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO LTD (KR) | 2017-03-09 | — | — | US | claimed |
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-01-14 | — | — | US | disclosed |
| CN-117026626-A | Carbon fiber core copper wire and preparation method thereof | 江苏集萃碳纤维及复合材料应用技术研究院有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-117026626-A | Carbon fiber core copper wire and preparation method thereof | 江苏集萃碳纤维及复合材料应用技术研究院有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115142148-B | High-performance binary polyacrylonitrile-based carbon fiber precursor and preparation method thereof | 东华大学 | 2023-03-21 | — | — | CN | disclosed |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | disclosed |
| CN-115142148-A | High-performance binary polyacrylonitrile-based carbon fiber precursor and preparation method thereof | 东华大学 | 2022-10-04 | — | — | CN | disclosed |
| WO-2021080330-A1 | NICOTINAMIDE COMPOUND AND HERBICIDAL COMPOSITION COMPRISING COMPOUND | 한국화학연구원 | 2021-04-29 | — | — | WO | disclosed |
| US-20140088099-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | INFINITY PHARMACEUTICALS, INC. (US) | 2014-03-27 | — | — | US | disclosed |
| US-8604032-B2 | Chemical compounds, compositions and methods for kinase modulation | INFINITY PHARMACEUTICALS, INC. (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2571357-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | Intellikine, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130029984-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLIKINE, LLC (US) | 2013-01-31 | — | — | US | disclosed |
| WO-2013012918-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS INC. (US) | 2013-01-24 | — | — | WO | disclosed |
| US-20120059000-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | INFINITY PHARMACEUTICALS, INC. | 2012-03-08 | — | — | US | disclosed |
| WO-2011146882-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | INTELLIKINE, INC. (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355690-A9 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | HDAC1 1535/4885HDAC6 1117/4885THRB 733/4885 |
| US-20120059000-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | MAP3K13, AKT3, PIK3CA | HDAC1 620/4885HDAC6 854/4885THRB 2404/4885 |
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | MERTK, ERBB2, SRC | HDAC1 1535/4885HDAC6 1117/4885THRB 733/4885 |
| US-10125118-B2 | Heteroaryl compounds and their use as therapeutic drugs | MERTK, ERBB2, SRC | HDAC1 1535/4885HDAC6 1117/4885THRB 733/4885 |
| US-20140088099-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | MAP3K13, AKT3, PIK3CA | HDAC1 620/4885HDAC6 854/4885THRB 2404/4885 |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | HDAC1 1535/4885HDAC6 1117/4885THRB 733/4885 |
| US-20130029984-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PIK3CA, PIK3CD, PIK3CB | HDAC1 440/4885HDAC6 340/4885THRB 2231/4885 |
| US-20170066742-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | HDAC1 1535/4885HDAC6 1117/4885THRB 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.