Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9033663 | 0.98 | GAA (0.71) | GAASMN1; SMN2THRBLMNAHPGD | |
| SCHEMBL7839510 | 0.87 | GAA (0.76) | GAASMN1; SMN2THRBALDH1A1HDAC1 | |
| SCHEMBL19593551 | 0.85 | THRB (0.68) | GAASMN1; SMN2THRBLMNAALDH1A1 | |
| Ribose (Furanose) SCHEMBL502889 | 0.83 | GAA (0.54) | GAASMN1; SMN2THRBLMNAHPGD | |
| SCHEMBL1233991 | 0.81 | THRB (0.72) | SMN1; SMN2THRBLMNAALDH1A1HDAC1 | |
| SCHEMBL25328235 | 0.81 | THRB (0.77) | GAASMN1; SMN2THRBALDH1A1HDAC1 | |
| SCHEMBL14415899 | 0.81 | THRB (0.77) | GAASMN1; SMN2THRBLMNAALDH1A1 | |
| SCHEMBL28489211 | 0.80 | SMN1; SMN2 (1.00) | GAASMN1; SMN2LMNAHPGDALDH1A1 | |
| N-Hydroxymethylnicotinamide SCHEMBL352358 | 0.80 | THRB (1.00) | SMN1; SMN2THRBLMNAALDH1A1HDAC1 | |
| SCHEMBL83922 | 0.79 | HPGD (0.86) | GAASMN1; SMN2LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049674-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE | L'OREAL (FR) | 2025-02-13 | — | — | US | claimed |
| US-20240423888-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2024-12-26 | — | — | US | claimed |
| CN-118871078-A | Cosmetic or dermatological composition comprising at least a merocyanine and a hydrotrope | 欧莱雅 | 2024-10-29 | — | — | CN | claimed |
| EP-4447895-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2024-10-23 | — | — | EP | claimed |
| CN-118804735-A | Cosmetic and/or dermatological composition comprising at least one merocyanine and at least ascorbic acid and/or derivatives thereof | 莱雅公司 | 2024-10-18 | — | — | CN | claimed |
| CN-117913224-A | Negative electrode material, preparation method thereof and sodium ion battery | 碳一新能源集团有限责任公司 | 2024-04-19 | — | — | CN | claimed |
| WO-2023110772-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE | L'OREAL (FR) | 2023-06-22 | — | — | WO | claimed |
| WO-2023110763-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | L'OREAL (FR) | 2023-06-22 | — | — | WO | claimed |
| CN-109414382-B | Cosmetic composition containing 4- (3-ethoxy-4-hydroxyphenyl) butan-2-one and niacinamide compound | 莱雅公司 | 2021-12-10 | — | — | CN | claimed |
| CN-112315889-A | Eye essence cream and preparation method thereof | 姚佃文 | 2021-02-05 | — | — | CN | claimed |
| EP-3478253-B1 | LIQUID MIXTURE CONTAINING 4-(3-ETHOXY-4-HYDROXYPHENYL)BUTAN-2-ONE, A NIACINAMIDE COMPOUND, AND COSMETIC COMPOSITION CONTAINING SAME | OREAL (FR) | 2020-02-12 | — | — | EP | claimed |
| EP-3362436-A1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | Universiteit Antwerpen (BE) | 2018-08-22 | — | — | EP | claimed |
| WO-2017046133-A1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2017-03-23 | — | — | WO | claimed |
| US-20110046724-A1 | Expansible Biocompatible Coats Comprising a Biologically Active Substance | AVIDAL VASCULAR GMBH (DE) | 2011-02-24 | — | — | US | claimed |
| EP-2271396-A2 | EXPANSIBLE BIOCOMPATIBLE COATS COMPRISING A BIOLOGICALLY ACTIVE SUBSTANCE | Avidal Vascular Gmbh (DE) | 2011-01-12 | — | — | EP | claimed |
| WO-2009121565-A2 | EXPANSIBLE BIOCOMPATIBLE COATS COMPRISING A BIOLOGICALLY ACTIVE SUBSTANCE | AVIDAL VASCULAR GMBH (DE) | 2009-10-08 | — | — | WO | claimed |
| US-20050158271-A1 | Pharmaceutical applications of hydrotropic polymer micelles | AKINA, INC. | 2005-07-21 | — | — | US | claimed |
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | PURDUE RESEARCH FOUNDATION | 2003-02-13 | — | — | US | claimed |
| WO-2002030466-A2 | PHARMACEUTICAL APPLICATIONS OF HYDROTROPIC AGENTS, POLYMERS THEREOF, AND HYDROGELS THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2002-04-18 | — | — | WO | claimed |
| US-4204065-A | Soft quaternary surface active agents and method of using same | INTERX RESEARCH CORPORATION (US) | 1980-05-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050158271-A1 | Pharmaceutical applications of hydrotropic polymer micelles | SLC46A1, SLC5A6, NAMPT | GAA 905/4885SMN1; SMN2 1064/4885THRB 2096/4885 |
| US-20240423888-A1 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF | KRT18, PROC, DSC1 | GAA 1075/4885SMN1; SMN2 4554/4885THRB 4707/4885 |
| US-20250049674-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE | NAPRT, NAMPT, NNMT | GAA 1422/4885SMN1; SMN2 3761/4885THRB 4187/4885 |
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | HMGB2, HTT, ABCG2 | GAA 2447/4885SMN1; SMN2 1806/4885THRB 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.