Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033060 | 0.78 | MEN1 (0.35) | MEN1USP2HTTKMT2AKEAP1 | |
| SCHEMBL4644733 | 0.74 | MAOA (0.33) | MEN1KMT2A | |
| SCHEMBL27899887 | 0.73 | ALDH1A1 (0.47) | MEN1USP2HTTKMT2AKEAP1 | |
| SCHEMBL806281 | 0.72 | MAPT (0.35) | MEN1KMT2A | |
| SCHEMBL19398839 | 0.72 | MEN1 (0.33) | MEN1USP2HTTKMT2AKEAP1 | |
| SCHEMBL23647865 | 0.71 | CCNB2 (0.31) | — | |
| Ethane SCHEMBL27539333 | 0.71 | NLRP3 (0.33) | — | |
| SCHEMBL8436954 | 0.71 | BCL2L1 (0.42) | MEN1KMT2A | |
| SCHEMBL31158669 | 0.71 | HTR2A (0.33) | — | |
| SCHEMBL7792883 | 0.70 | MAOA (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847190-A1 | BICYCLICALLY SUBSTITUTED URACILS AND THE USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013167495-A1 | BICYCLICALLY SUBSTITUTED URACILS AND THE USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-11-14 | — | — | WO | disclosed |