Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 17/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553362 | 0.89 | KCNH2 (0.44) | CXCR3 | |
| SCHEMBL451131 | 0.88 | NPC1 (0.52) | CXCR3 | |
| SCHEMBL450061 | 0.87 | CXCR3 (0.54) | CXCR3 | |
| SCHEMBL450858 | 0.85 | SMN1; SMN2 (0.57) | CXCR3 | |
| SCHEMBL1553760 | 0.85 | CXCR3 (0.54) | CXCR3 | |
| SCHEMBL447902 | 0.84 | PTGS2 (0.49) | — | |
| SCHEMBL453737 | 0.84 | SMN1; SMN2 (0.58) | — | |
| SCHEMBL452172 | 0.82 | ALDH1A1 (0.61) | CXCR3 | |
| SCHEMBL450044 | 0.82 | MEN1 (0.47) | CXCR3 | |
| SCHEMBL452947 | 0.80 | PIK3CD (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521746-B1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2011-04-27 | — | — | EP | claimed |